Protein switch engineering.
CIDER has developed a unique bio-engineering platform that produces enzyme-based protein switches with the desired properties for novel diagnostic, therapeutic and bioengineering applications.
Introducing
FleX Switch™
These protein biosensors are used to create molecular and biochemical tests for potentially any application, from high-volume centralised laboratories through to point-of-care testing and wearable devices.
They utilise a modular architecture that allows conversion of potentially any sensing input into potentially any reporting output.
The FleX SwitchTM system will empower assay developers to design deeply innovative products for the medical and industrial industries.
CIDER takes a departure from the traditional biotechnology model that collected natural proteins and built hardware solutions around them.
CIDER technology enables the construction of bespoke biosensors tailored to specific ligands. Switch specificity can be targeted towards ions, small molecules, lipids, peptides, proteins, DNA and RNA.
Ions
Develop highly sensitive assays for detecting critical ions in patient samples, providing rapid and accurate diagnostic information for conditions like electrolyte imbalances.
Small Molecules
Design precise biosensors for small molecules such as therapeutic drugs or cortisol, enhancing the accuracy of drug monitoring and stress markers.
Proteins
Create targeted assays for biomarkers like CRP or ALT, enabling early detection and monitoring of liver function diseases or inflammatory disorders.
DNA
Build cutting-edge assays for DNA and RNA, facilitating the identification of infectious diseases, cancer or genetic mutations, and advancing personalised medicine.
DESIGN WITH FLEXSWITCH
Unparalleled versatility,
customization, and speed
FleX SwitchTM offers unparalleled versatility, customization, and speed of protein switch engineering.
Unlike traditional approaches, our technology enables the construction of bespoke biosensors tailored to output preferences.
This level of customization allows us to address the unique needs of any application and seamlessly integrate with various detection and application platforms.
The output that can be produced from the interaction between the target analyte and the switch includes luminescence, fluorescence, electric current, changes in absorption or custom defined enzymatic activity.
Patented Design Process
Design process is fast and simple.
Fast
Reduce reagent development time by up to 50%.
Incredibly Simple Assays
Enabling production of a homogenous assay containing only two components – one protein and one substrate.
Extremely Low Cost of Manufacturing
Orders of magnitude lower than any other manufacturing method.
About Us
Founder
CIDER was founded in 2024 by Professor
Kirill Alexandrov.
Kirill Alexandrov
Founder
Kirill has extensive experience in molecular, structural, and synthetic biology, with over 25 years of research experience and >160 publications. He is an NHMRC fellow and Professor of Synthetic Biology at Queensland University of Technology. He is the inventor of key patents underlaying CIDER.
